Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Adamantoic Acid is an inhibitor of chorismate mutase activity and hydroxyphenylpyruvate synthase. It inhibits TTR conformational changes facilitating amyloid fibril formation.
參考文獻
Baures, P. et al.: Bioorg. Med. Chem., 6, 1389 (1998); Christopherson, R. et al.: Biochem., 24, 1116 (1985); Chao, Herbert S. & Berchtold, G.: Biochem., 21, 2778 (1982)