Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
應用
Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2uM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.
參考文獻
Macleod, K.M., et al.: Mol. Pharmacol., 32, 59 (1987), Mulsch, A. J.: J. Pharmacol. Exp. Ther., 247, 283 (1988), Mulsch, A., et al.: Naunyn-Schmiedeberg's Arch. Pharmacol., 340, 119 (1989), Light, D.B., et al.: Science, 243, 383 (1989), Beasley, D., et al.: J. Clin. Invest., 87, 602 (1991)
滬ICP備17019645號
400-821-0725
