Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應用
N,N'-Bis[4-chloro-3-trifluoromethylphenyl]urea is a compound related to that of Sorafenib (S676850) which is a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis.
參考文獻
Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),
滬ICP備17019645號
400-821-0725
