3,5-Bis(trifluoromethyl)benzyl Bromide is used as a reagent in the synthesis of [(chlorophenyl)benzylamino]propanamides as cholesteryl ester transfer protein (CETP) inhibitors. Also used as a reagent in the synthesis of substituted dihydropyridopyrazinedione derivatives as γ-secretase modulators in the treatment of Alzheimer's disease.
參考文獻
Zhao, D., et al.: Chin. Chem. Lett., 25, 299 (2014); Rombouts, F., et al.: PCT Int. Appl. WO?2013171712?A1?20131121. Nov 21, 2013
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