Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
(4-?tert-?Butyl-?2,?6-?dimethylphenyl)?acetonitrile (Xylometazoline EP Impurity C) is an impurity of Xylometazoline (X749950), a vasoconstrictor involved in signal transduction, also used as a nasal decongestant. May be used in treatments involving ischemic injury due to the ability to shift energy metabolism from mitochondrial to glycolysis (2).
參考文獻
1. Fliri, A. et al.: J. Med. Chem. 2009 Dec 24;52(24):8038-46.2. Gohil, V. et al.: Nat Biotechnol. 2010 Mar;28(3):249-55.
滬ICP備17019645號
400-821-0725
