英文名稱
6-Desacetyl-6-bromo-N-Boc Palbociclib
4-[6-[(6-溴-8-環戊基-7,8-二氫-5-甲基-7-氧代吡啶并[2,3-d]嘧啶-2-基)氨基]-3-吡啶
Smiles Code
CC1=C(Br)C(=O)N(C2CCCC2)c3nc(Nc4ccc(cn4)N5CCN(CC5)C(=O)OC(C)(C)C)ncc13
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
6-Desacetyl-6-bromo-N-Boc Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.
滬ICP備17019645號
400-821-0725
