Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
4’,5’-Dihydrocephradine is an impurity in the synthesis of Cephradine (C261800), a first generation cephalosporin antibiotic. Cephradine has broad spectrum of bactericidal activity against infections caused by Streptococcus, Staphylococcus, Diplococcus pneumoniae, Escherichia, Klebsiella, Salmonella, and indole-negative Proteus.
參考文獻
Poutsiaka, J.W. et al.: Prog. Chemother. (Antibacterial, Antiviral, Antineoplast.), Proc. Int. Congr. Chemother., 2, 142 (1974); Florey, K. et al.: Anal. Prof. Drug Subs., 5, 21 (1976);
滬ICP備17019645號
400-821-0725
