Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Labelled Duloxetine, an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.Current lot is 97% d7 with no d0, d1 or d2.
參考文獻
Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)