Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.
參考文獻
Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)
滬ICP備17019645號
400-821-0725
