Ethyl 4-(4-Fluorophenyl)-3-oxobutanoate is used in the synthesis of novel pyridinone derivatives as non-nucleoside reverse transcriptase inhibitors with high potency against NNRTI-resistant HIV-1 strains. Also used in the structural evaluation of 2-substituted 5-hydroxyindole 3-carboxylates as potent inhibitors of human 5-lipoxygenase.
參考文獻
Li, A. et al.: J. med. Chem., 56, 3593 (2013); Karg, E. et al.: J. Med. Chem., 52, 3474 (2009);
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