Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
4-(3-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
參考文獻
Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)
滬ICP備17019645號
400-821-0725
