5-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
中文名稱
5-羥基奧美拉唑
分子式
C17H19N3O4S
分子量
361.42
Smiles Code
COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(CO)c(OC)c3C
存儲條件
-86°C
性狀
White to Pale Brown Solid
溶解性
Chloroform (Slightly), Methanol (Slightly)
類別
Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
應用
5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.
參考文獻
Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)
滬ICP備17019645號
400-821-0725
