Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants that displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. ISL induces quinone reductase-1, a phase II enzyme that deactivates radicals and electrophiles, with a concentration required to double activity (CD) value of 1.8 uM in murine hepatoma cells.
參考文獻
Agrawal, R., et al.: Food Chem. Toxicol., 36, 975 (1998), Baba, M., et al.: Biol. Pharm. Bull., 25, 247 (2002), Chowdhury, S., et al.: Anticancer Res., 25, 2055 (2005),
滬ICP備17019645號
400-821-0725
