Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides; Semi-Synthetic;
應用
Lignan P is a metabolite of Etoposide (E933750), which is a DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. It is also an Antineoplastic.
參考文獻
Burden, D.A., et al.: J. Biol. Chem., 271, 29238 (1996), Joel, S., et al.: Cancer Treat. Rev., 22, 179 (1996),