(1R,3S,5R)-5-Methyl-2-azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester can be used to prepare indole analogs as complement factor D?inhibitors for treating age-related macular degeneration. It can also be utilized to synthesize hepatitis C virus inhibitors.
參考文獻
Altmann, E., et al.: PCT Int. Appl. WO?2012093101?A1?20120712 (2012); Lavoie, R., et al.:?PCT Int. Appl. WO?2011059887?A1?20110519 (2011); Pack, S. K., et al.:?PCT Int. Appl. WO?2011059850?A1?2011051 (2011)
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