Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
N-Methyl-4-[1-(4-chlorophenyl)-1-phenylethoxy)hexahydroazepine (Clemastine EP Impurity B) is an impurity in the synthesis of Clemastine Fumarate (C568500); a H1 histamine receptor antagonist and antihistaminic.
參考文獻
Froehlich, L., et al.: Pharmazie, 51, 409 (1996); Weidmann, et al.: Boll. Chim. Farm., 106, 467 (1967); Gober, B., et al.: Pharmazie, 43, 539 (1988); Breccia, A., et al.: Curr. Ther. Res., 49, 622 (1991); Schran, H., et al.: J. Clin. Pharmacol., 36, 911 (1996); Wakabayashi, T., et al.: Jpn. Kokai Tokkyo Koho.?JP?52136165?A?19771114. Nov 14, 1977
滬ICP備17019645號
400-821-0725
