Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
應用
1-Methyl-2-(methylthio)imidazole (Methimazole USP Related Compound C) is an impurity of Methimazole (M260300), a thiourea antithyroid agent that prevents iodine organification, thus inhibiting the synthesis of thyroxine.
參考文獻
Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1979), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984), Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1991),
滬ICP備17019645號
400-821-0725
