Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Nicorandil is a nitric oxide donor and ATP-sensitive potassium channel opener (1,2,3). A study showed that Nicorandil is able to protect against stress-induced cell death in dystrophin-deficient cardiomyocytes and also preserve cardiac function in the mdx mouse heart subjected to ischemia and reperfusion injury (4).
參考文獻
(1) Ma, C., et al.: J Pharm Biomed Anal. (2008) 47:677(2) Sudo, H., et al.: Biol Pharm Bull. (2008) 31:2079(3) Iida, S., et al.: Br J Clin Pharmacol. (2008) 66:352-65(4) Afzal, M. Z., et al.: J Cardiovasc Pharmacol Ther. (2016) 21:549-562
滬ICP備17019645號
400-821-0725
