Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
應用
ONO-SA 246 is a metabolite of Landiolol (L173900), which is an ultra-short acting beta blocker that is used to treat patients with cardiac arrhythmias. It is also used for treatment of tachycardia during anasthesia.
參考文獻
Atarashi, H., et al.: Clin. Pharmacol. Ther., 68, 143 (2000); Harasawa, R., et al.: J. Cardiothor. Vasc. An., 20, 793 (2006); Hashimoto, Y., et al.: Biol. Pharm. Bull., 32, 121 (2009);