3-Oxo Atorvastatin tert-Butyl Ester is a Boc-protected oxo-derivative of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin can also lower both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
參考文獻
Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)
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