Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Paclitaxel related compound C. Paclitaxel analogs were tested for tubulin assembly and cytotoxicity, and were shown to retain potency similar to Paclitaxel. Paclitaxel EP Impurity C.
參考文獻
Ojima, I., et al.: J. Med. Chem., 38, 3891 (1995), van Asperen, J., et al.: J. Pharm. Sci., 86, 881 (1997), Fellner, S., et al.: J. Clin. Invest., 110, 1309 (2002), Beckers, T., et al.: Drugs Future, 28, 767 (2003), Kemper, E., et al.: Clin. Cancer Res., 9, 2849 (2003),