Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a useful synthetic intermediate in the synthesis of Ibrutinib (I124970); a highly selective BrutonтАЩs tyrosine kinase (BTK) irreversible inhibitor.
參考文獻
MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011); Li, X., et al.: J. Med. Chem., 58, 9625 (2015)
滬ICP備17019645號
400-821-0725
