Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Pomalidomide M16 is a derivative of Pomalidomide (P688200), an amino derivative of Thalidomide (T338850), which is a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
參考文獻
Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999); Gupta, D., et. al.: Leuk., 15, 1950 (2001); Lokhorst, H., et. al.: N. Engl. J. Med., 373, 1207 (2015)
滬ICP備17019645號
400-821-0725
