Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Promethazine Sulfone, is a metabolite of Promethazine (P757000), which is a drug from antihistamine family. It has strong sedative effects and in some countries used for the treatment of insomnia. It has also antiemetic and anticholinergic properties.
參考文獻
Edge, W., et al.: J. Pharm. Pharmacol., 5, 279 (1953), Huang, et al.: J. Pharm. Sci., 59, 772 (1970), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 5, 429 (1976)