Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
應用
Regorafenib Dipyrimidine is an impurity of Regorafenib(R143000); which inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
參考文獻
Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000),
滬ICP備17019645號
400-821-0725
