Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
應用
4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
參考文獻
Sasaki, H., et al.: J. Med. Chem., 49, 7854 (2006);
滬ICP備17019645號
400-821-0725
